High school can really get under your skin, as Emile Hirsch is discovering in this exclusive first look image from the horror-comedy Lice.

Hirsch stars in the film, which is in post-production, as a burned-out science teacher, Mr. Shanker, whose school is thrown into chaos when a parasite begins infecting the student body, turning the teenagers into maniacs. The uninfected students and staff are left to reign in the chaos and get to the bottom of the illness — a possible government experiment gone wrong. And, in a first look at the film, Hirsch’s Mr. Shanker is clearly not having a good time.

Elsewhere in the movie, from director Jonathan Bensimon, are the overwhelmed and over-imbibing Principal Van (Justin Long) and Detective Sikorski (Kevin Connolly), who is working outside the school grounds to contain the outbreak before it consumes the entire town.

Connolly is pulling double duty, producing under Connolly’s ActionPark Productions banner, with Jeremy Alter and Gary Goldman also acting as producers.

Anthony Musella and Shaun Harris wrote the screenplay for Lice, which is for sale out of the Toronto Film Festival with Highland Film Group handling international sales.

By Kevin Cassidy, The Hollywood Reporter